Why are DHEA & Testosterone Important? 

 

Testosterone is a male hormone, right? True, but females need it just as much as males do, just in smaller amounts. Not only is necessary for a healthy libido and sexual satisfaction, but it is also essential for bone health, brain health, muscle health, and heart health. It needs to be in balance with the other female hormones, estrogen, and progesterone (sex steroids), thyroid hormones, as well as our major stress hormone, cortisol, in order to function optimally. The Androgen DHEA is a feel-good hormone. It gives one a feeling of well being, libido, good sleep, muscle strength, and exercise tolerance.

 

What are the common symptoms of DHEA deficiency? 

Common symptoms of DHEA deficiency include reduced sex drive, reduced sexual sensitivity, difficulty achieving orgasm, painful intercourse, low mood and excessive anxiety, poor coping ability, reduced muscle tone and strength, joint pain, back pain, dry skin, poor memory or concentration and urinary incontinence. The symptoms can overlap with hormonal and other medical conditions. Thus, androgen deficiency often goes under-diagnosed and is not often thought to be relevant in females.

 

Cortisol Steal

So where does it all go wrong and why are we seeing so many women, young and old, with deficiency these days? Cortisol steal. This is exactly what it sounds like. Cortisol is stealing the substrates that our sex steroids and DHEA need to be formed because it is being produced in excess. DHEA becomes depleted and because this is upstream from testosterone (and estrogen), these downstream hormones also become depleted. So it’s the stressed women that get more hormonal issues. It is not the hormones’ fault. They are just responding appropriately to other imbalances in the body. Why would you need to reproduce or have sex for that matter, if you are running away from a lion?

 

Cortisol Steal

 

Stress and Hormones

The body interprets internal and external stress as the same thing. It doesn’t know the difference between having a fight with someone vs candida overgrowth in the gut, for example. It responds by releasing cortisol and other stress hormones and neurotransmitters from the adrenal glands. When cortisol is produced in excess, the hypothalamus in the brain perceives a threat. It switches off signals to the adrenals and cortisol is no longer produced. Alongside this, high cortisol triggers DHEA release, which tries to balance the high cortisol. With DHEA and cortisol levels low, the patient experiences stage 3 adrenal fatigue. The new term for this is HPA axis dysfunction/ dysregulation. 

 

Replacing DHEA and Testosterone in Women

DHEA and testosterone can be replaced alone, or alongside each other in women. It should be ensured that the other female hormones are also optimal. In our practice, we prescribe bioidentical hormones, which are hormones that behave in an exact way as our own hormones. They are still laboratory-made but are chemically identical to our hormones. The bad rap that hormone replacement has is from synthetic hormones, which confuse our hormonal systems – like putting the wrong key into a lock. Testosterone is most often prescribed topically, or in certain cases intramuscularly/ subcutaneous. DHEA is most often prescribed sublingually or by mouth, but can also be given topically.

 

The key to safe hormone replacement is testing your levels (24 hour urine hormone is the best test for this, but blood levels can be used when resources are limited). Once on the treatment, levels should be monitored by an experienced health care professional in order to find the dose that is right for you. This can vary tremendously between women, depending on genetics, underlying factors that caused the hormone deficit and lifestyle (a very active woman requires more DHEA or testosterone, often). You can find your optimum dose by looking at your levels alongside your symptoms. 

 

What else can you do to improve your levels besides taking hormones?

Hormone replacement is not the only answer but in every case, should be done alongside root cause treatment and lifestyle changes. Hormone replacement does not fix the adrenals and other hormones. It is just another patch if done alone. Some women even feel worse on hormones, which tells us we need to work on these root causes.

 

Other Lifestyle Improvements

So what can you do to help these hormones in your day to day life? Your overall aim is to decrease inflammation and stress on the HPA axis.

 

Diet

An anti-inflammatory diet is a good place to start. Many hormone disturbances start in the gut, because of a constant onslaught of foods that increase inflammation, upregulate our immune system, change our microbiome, and impact our gut-brain connection. Sugar, carbohydrates, and dairy are big contributors to poor hormone health.

 

Exercise

Make sure you are getting exercise that is appropriate for your condition. Don’t run a marathon when your adrenals are shot.

 

Sleep

Make sure you get at least 7-8 hours of sleep each night. Good sleep hygiene is essential and your health care professional may recommend supplements and medications for this.

 

Stress Management

Make sure you are identifying and managing stress – we cannot always change our stressful circumstances but we can change how we perceive them and what we do every day to find our calm.

 

We recommend 2 books to find out more: The Hormone Handbook by Dr. Thierry Hertoghe; and, What You Must Know About Women’s Hormones: Your Guide to Natural Hormone Treatments for PMS, Menopause, Osteoporis, PCOS, and More by Dr. Pamela Wartian Smith.

 

About the author:

One of Dr. Michelle’s greatest passions in life is to help people help themselves. She understands that your current health tells a story and that when you have symptoms of disease, your body is already out of balance. She believes that we should not have to settle for anything other than our most vital self and that her job is to figure out how to put you back on track. To book an appointment with Dr. Michelle, contact [email protected]

Those who live with food sensitivities understand that these medical issues are very real and can greatly impact patients’ lives. However, there is much more to food sensitivities that the pain and embarrassment that can come from the typical bloating, nausea, and diarrhea associated with these ailments. In fact, food sensitivities are often the cause of widespread inflammation and can go hand in hand with gut bacterial imbalances, mineral and vitamin deficiencies, obesity, and autoimmune disorders.

 

What Are Food Sensitivities?

Food sensitivities, aka food intolerances, are any set of adverse reactions to ingested food. Unlike a true food allergy, food sensitivity may be linked to any component of any food. This includes things like artificial colours, sweeteners, preservatives, and any number of additives.


A food sensitivity is often chronic, meaning the symptoms may be slow in onset and last for an extended duration. Gluten-sensitive individuals, for example, may suffer from gastrointestinal symptoms for weeks after eating a bagel but these symptoms often don’t first appear until 24-78 after ingestion.

 

Is Testing Available for Food Sensitivities?

Traditional medicine does not offer much in the way of food sensitivity testing. Illnesses are tested through tissue biopsies in the intestinal tract. Illnesses like gluten sensitivity associated with celiac disease, Functional Medicine provides other options – specialized laboratories offer testing of mouth swabs and stool samples in order to ascertain exact food sensitivities. Functional Medicine physicians often make use of these facilities to aid in precise diagnosis of their patients’ diseases. These laboratories can help confirm sensitivity to proteins such as gluten.

 

How Are Food Sensitivities Related to Inflammation?

Inflammation is part of the immune response, the body’s normal answer to harmful invasive organisms. Inflammation is characterized by redness, swelling, irritation, and increased temperature. Unfortunately, the immune system is not always able to properly distinguish a real threat from a relatively harmless substance. When a person with a food intolerance ingests a triggering food, the gastrointestinal tract becomes inflamed. This often happens as a result of the overgrowth of “bad” bacteria and yeast. These microorganisms compete with and kill off the normal, helpful gut bacteria.1

 

Systemic Inflammation

This inflammation may become systemic, or spread throughout the body. And, since food sensitivities are chronic, the symptoms may not be immediately apparent. In the meantime, the patient might eat more of the offending food, unaware that anything is wrong. This sends the immune system into overdrive and inflammation increases.2

 

One of the best measures of inflammation is called C-reactive protein (CRP). This compound increases along with inflammation and can be quantified by a simple blood test. Multiple studies have demonstrated a link between CRP levels and “Western” diets rich in carbohydrates and fats. These diets often contain foods that are common triggers for food-sensitive individuals.

 

CRP Levels

For example, a study published in 2017 found that European children who consumed diets full of sugars and processed foods had higher CRP levels than children who ate many fruits and vegetables.3 Furthermore, an analysis published in 2016 stated that “Consumption of a healthy dietary pattern was associated with significant reductions in CRP.”4

 

Stress and Anxiety

Additional factors in food sensitivity-related inflammation are stress and anxiety. Patients suffering from symptoms of food sensitivity often experience stress and anxiety from a combination of their painful symptoms and worry. This stress contributes to the inflammation they experience and starts a cycle that is almost impossible to break without medical intervention. Other circumstances that contribute to inflammation include heavy metal toxicity and the use of non-steroidal anti-inflammatory drugs like ibuprofen and aspirin.1

 

How Can Functional Medicine Help?

Dr. Lynne Murfin helps her patients manage their food sensitivities and decrease their symptoms (and inflammation) in a number of ways. Along with confirmation of suspected food sensitivities by diagnostic testing, Dr. Murfin will look for other contributing factors, like unacceptable levels of heavy metals and nutrient deficiencies. Each factor is addressed in order to rebuild a healthy gut.

 

Inadequate nutrient levels are actually a frequent problem with food-sensitive patients. Many patients realize that they have some sort of sensitivity and avoid triggering foods, such as dairy products. However, these patients often have malabsorption issues due to their inflamed guts. These issues can lead to low levels of calcium and vitamin D.5 Part of the Functional Medicine approach is to replace these crucial vitamins and minerals. Furthermore, supplements and minerals, such as glutamine and zinc, are very helpful in gut repair.

 

Another critical step in resolving the inflammation that occurs with food sensitivity is to fix it where it starts – the gut. Dr.Murfin can prescribe specific probiotics to flood a patient’s gut with good bacteria – that kind that assists in digestion. These probiotics are tailored to each patient’s unique situation.

 

 

Next Steps:

A good Functional Medicine physician is an invaluable source of healthy lifestyle advice. Proper diet and exercise are critical components of being both inflammation-free and healthy in general. Multiple studies have shown this to be the case. One such study appeared in the International Journal of Obesity in 2017. The authors found that CRP levels in obese pregnant women fell significantly when the participants adhered to a program of physical activity and carbohydrate restriction.6 Additionally, a separate 2017 study showed reduced CRP levels in mice who were given lycopene and tomato powder, one hallmark of a healthy diet.Beyond diet and exercise, stress levels are also intimately tied to gut health and food sensitivities. This is one reason why Dr. Murfin provides the teaching of stress-relieving techniques and lifestyle education in her practice.


Those suffering from food intolerances, obesity, and inflammation, whether seen or unseen, can find hope in Functional Medicine treatment. This holistic approach aids in balancing the microecosystem of the gut and helps patients not only be better,  but feel better too.

 

References:

https://www.ncbi.nlm.nih.gov/pubmed/28012610
https://www.ncbi.nlm.nih.gov/pubmed/28129482
https://www.ncbi.nlm.nih.gov/pubmed/25115507
https://www.ncbi.nlm.nih.gov/pubmed/28042611
http://www.jpsbr.org/index_htm_files/JPSBR14RS5036.pdf
https://www.ncbi.nlm.nih.gov/pubmed/28008257
https://www.ncbi.nlm.nih.gov/pubmed/28154742
https://www.ncbi.nlm.nih.gov/pubmed/28103130
https://www.ncbi.nlm.nih.gov/pubmed/25218407
10 https://www.ncbi.nlm.nih.gov/pubmed/8637392
11 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579978

 

About Dr. Murfin:

Dr. Murfin is wholeheartedly focused on her life’s mission to help people heal and achieve extraordinary outcomes. She believes that health is more than merely the absence of disease. It is a total state of physical, mental, emotional, spiritual, and social wellbeing through the creation of a whole and meaningful life. Dr. Murfin leaves no stone unturned to determine the root cause of illness or imbalance.

The things you eat drastically affect gut health. Your diet is crucial in this. Food gives you energy and affects your body’s ability to stop disease.

 

“Let food be thy medicine, and let medicine be thy food.”

– Hippocrates

 

Healing Your Gut

 

Improving gut microflora is the first step in healing your gut. Lifestyle factors disturb your gut’s microbiome. These factors can be regular consumption of processed foods, frequent antibiotic use, lack of sleep, and more. Good bacteria may restore your body’s balance but if you suffer from serious gut conditions, there are treatments available for you.

 

Dr. Lynne Murfin is trained in traditional methods. She makes use of traditional Western Medicine and Functional Medicine facets in her management of patients. The Linden & Arc Vitality Institute team of functional medicine physicians offers a Collaborative Care Model designed to offer the highest level of care. We leave no stone unturned.

 

What’s Your Condition?

 

If you have been diagnosed with any of the following conditions, contact us today and let us get to the root cause.

  • Irritable Bowel Syndrome (IBS)
  • Small intestinal bacterial overgrowth (SIBO)
  • Inflammatory Bowel Disease (IBD)
  • Celiac disease
  • Crohn disease
  • Ulcerative colitis
  • Diverticulitis
  • Malabsorption
  • Short bowel syndrome
  • Intestinal ischemia
  • Gastroesophageal reflux disease (GERD)
  • Peptic ulcer disease,
  • Hiatal hernia

 

Lifestyle Changes

 

Remember, not every lifestyle change has to be a huge, profound one to be healthy. Small changes to your routine can open up a wealth of benefits. By making one tiny health-promoting change in your routine each day, you will soon find yourself firmly on the path to a wholesome, healthy lifestyle.

 

Gut health is important to us. We are here to reinforce you through your health journey but you will also need a strong support system on the outside. Rely on friends and family who understand your needs.

 

About Dr. Murfin:

Dr. Murfin is wholeheartedly focused on her life’s mission to help people heal and achieve extraordinary outcomes. She believes that health is more than merely the absence of disease. It is a total state of physical, mental, emotional, spiritual, and social wellbeing through the creation of a whole and meaningful life. Dr. Murfin leaves no stone unturned to determine the root cause of illness or imbalance.

 

The aging process is something that humans continue to fight with fervor. As a woman, our drive seems to focus on exterior appearance and we alter our true selves to meet the world. Conditioning is why we do this. Click here to read a fascinating article displays the journey of author, Karen Hines and her path to going grey. This empowering journey focuses on her exterior self just as she is.

 

The Healthy Aging Process

 

There is such a thing as healthy aging. At Linden & Arc Vitality Institute, science allows us to understand the aging process while functional medicine is how we treat it. Our Physicians and Nurse Practitioners spend time with our patients. They listen to their histories and look at the interactions among genetic, environmental, and lifestyle factors. These factors that can influence long-term health and complex, chronic disease. In this way, functional medicine supports the unique expression of health and vitality for each individual. If you are visiting our clinic, you can expect an in-depth analysis of your health. This includes history, diet, exercise, sleep, genetics, stress levels, and your nutrient and hormone status. We examine this wealth of information through a systems-lens. It allows our physicans to begin addressing interrelated factors that are currently out of balance.

 

If you would like to understand your aging process and feel empowered by this stage of life, contact us at [email protected] to book a consultation.

One vital component of your health that you might be neglecting is precious sleep. It is absolutely critical for both your short and long term health, and in our modern society, millions of people don’t get sufficient sleep. It’s well known that the ideal amount for optimal health is eight hours. Truthfully, the amount needed varies from person to person. Everybody is different and individual factors like age, overall health, stress level, and activity level can heavily influence how much you actually need.

 

Sleep Quality & Circadian Rhythm 

When it comes to sleep, quality is just as, if not more, important than quantity. Spending nine hours tossing and turning without ever entering deep sleep will not leave you refreshed and ready to go in the morning. What you need is an adequate amount of REM (rapid eye movement) each night. This is one of the deepest sleep phases where you experience your most vivid dreams.

 

Circadian rhythm or individual internal clock controls the sleep cycle. They developed in our ancestors in response to the natural day/night and seasonal cycles of the earth. It’s the reason why humans aren’t innately nocturnal and tend to be active during the day. These modern times can throw off your circadian rhythm. Artificial lighting, days spent working indoors, an unnatural diet, and night shift work may all contribute to a disordered internal clock. A variety of consequences – ranging from mild fatigue and depression to seasonal affective disorder (SAD) to even worse – can result from living with an out of balance circadian rhythm (1).


Even breaking your sleep cycle by frequently getting up to urinate during the night may cause depression (2). However, there are several steps you can take to get high-quality sleep and maintain a balanced circadian rhythm. 

 

Tip 1: Be Careful with Caffeine

Chances are that you consume at least some caffeine almost every day. While coffee is the most obvious culprit, caffeine is also present in many sodas, teas, and chocolate products. It’s no big deal to enjoy a morning java, but try to limit your intake. Even more importantly, avoid consuming caffeine past about mid-morning. The effects of caffeine can last seven hours or more, so it’s important that it’s all out of your system by bedtime. In fact, a 2014 study reinforced what we pretty much already knew, caffeine can significantly disturb your sleep (3).

 

Tip 2: Eat Dinner About 4 Hours Before Bed

You certainly don’t have to grab the early bird buffet special at 4 pm, but neither should you eat dinner at 10 pm and hit the sack one hour later. That’s because your body breaks down carbohydrates, or sugars, over time. You don’t need a sugar spike for energy while you’re sleeping, and an increase in blood glucose can actually cause you to have fitful, shallow sleep. Your best bet is to eat a dinner containing complex carbohydrates, like starch, about four hours before going to sleep. This will allow your body time to breakdown the carbs, giving you adequate energy for your remaining time awake while avoiding the middle of the night glucose spike.

 

Screen Time
Don’t Sleep at the Screen!

 

Tip 3: Limit Your Screen Time

If you fall asleep with a laptop or smartphone, you’re certainly not alone. Still, this type of screen time is a habit worth breaking. Computer monitors, televisions, and phone screens give off blue light, which interferes with the action of melatonin. Melatonin is a hormone that promotes sleepiness and helps you actually get to sleep. Blue light tricks your body into believing it’s still daylight outside and not yet time for sleep. Remember, your body’s systems haven’t caught up with modern technology. Do yourself a favour by discontinuing screen time at least two hours before bed.

 

Tip 4: Make Your Bedroom Sleep Hygienic

Just like you practice oral hygiene by brushing your teeth before bed, you need to observe sleep hygiene for a good night’s sleep. This means dedicating your bedroom to sleep and limiting distractions. Keep it nice and dark, as studies have shown a connection between melatonin levels and more light exposure, and don’t let the temperature get higher than about 21 degrees C– not a problem during the Albertan winters (4). Finally, try to insulate yourself from any unnecessary noise so that you’re not prematurely roused from restful sleep.

 

Tip 5: See Your Functional Medicine Doctor

Dr. Lynne Murfin treats all sorts of sleep disorders and can help discover the cause of your issue. Her training and experience are extensive. While there are many different things that can upset your circadian rhythm, there are also many treatments available, many of them natural.

For example, the stress response (“fight or flight”) has a huge effect on sleep quality, but this can be addressed in a variety of ways. Mind-body exercises guided by Dr. Murfin or her lifestyle educator can help reduce the stress and anxiety, and supplements.

 

Supplements for Sleep

Taking supplements for sleep is another option your functional medicine doctor may recommend. Supplemental B12 taken upon arising in the mornings may “reset” your stress response mechanism. In fact, vitamin B12 shows to have an effect on stress hormones in lab rats (5).

 

Another supplement that has shown promising results is valproic acid. This compound, in low doses, demonstrated an ability to reduce depression and restore circadian rhythm in a patient with an associated disorder (6).

 

Hormones for Sleep

Additionally, the use of hormones under Dr. Murfin’s direction can aid you in getting consistent, good sleep. If you’re not producing enough melatonin, small doses of this hormone could help in reducing your sleep latency, or the time it takes you to fall asleep. Melatonin is vital to the circadian rhythm. A study published in the journal Sleep Science even showed a correlation between low melatonin and the development of dementia in elderly patients (7).

 

Other substances that can have a positive effect include serotonin, gamma-amino butyric acid (GABA), and the female sex hormone progesterone. These compounds all frequently become imbalanced by a number of factors and need correction. For example, progesterone may protect against developing obstructive sleep apnea, a common sleep disorder (8)

 

GABA is a neurotransmitter involved in sleep maintenance. Low amounts of GABA have an association with insomnia, but fortunately, GABA supplements are available (11). Progesterone levels may drop during menopause, but research has shown that hormone therapy can result in better sleep (9).

 

Serotonin also plays its part in sleep, specifically maintenance. This neurotransmitter makes sure that you stay asleep long enough to truly rest. Serotonin has long been recognized to have a role in depression, with low levels contributing to depressive symptoms. It’s now known that serotonin can also directly affect the adrenal glands, crucial components in the stress response (10).

Controlling your stress response is a vital part of getting good sleep.


Consult a Qualified Physician

 

All neurotransmitters and hormonal supplements should be taken under the close monitoring of a qualified physician. Dr. Murfin can assist you in getting the best sleep possible. Lifestyle changes, nutrition support, and supplements may all contain the answers to your difficulties. Just remember – the road to good, and continued health – starts with you.

 

References:

https://www.ncbi.nlm.nih.gov/pubmed/28012610
https://www.ncbi.nlm.nih.gov/pubmed/28129482
https://www.ncbi.nlm.nih.gov/pubmed/25115507
https://www.ncbi.nlm.nih.gov/pubmed/28042611
http://www.jpsbr.org/index_htm_files/JPSBR14RS5036.pdf
https://www.ncbi.nlm.nih.gov/pubmed/28008257
https://www.ncbi.nlm.nih.gov/pubmed/28154742
https://www.ncbi.nlm.nih.gov/pubmed/28103130
https://www.ncbi.nlm.nih.gov/pubmed/25218407
10 https://www.ncbi.nlm.nih.gov/pubmed/8637392
11 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579978

 

About Dr. Murfin:

Dr. Murfin is wholeheartedly focused on her life’s mission to help people heal and achieve extraordinary outcomes. She believes that health is more than merely the absence of disease. It is a total state of physical, mental, emotional, spiritual, and social wellbeing through the creation of a whole and meaningful life. Dr. Murfin leaves no stone unturned to determine the root cause of illness or imbalance.

Brain Health and treating patients with Alzheimer’s and neurodegenerative conditions is a new frontier for Functional Medicine. Dr. Neil Nathan, MD’s book review of Dr. Dale Bredesen, MD’s “The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline explains and gives hope. Dr. Dale E. Bredesen MD, an internationally recognized expert in neurodegenerative diseases developed a highly effective protocol named The Bredesen ReCoDe.

 

The Bredesen ReCoDe for Alzheimer’s

 

The ReCoDe in Bredesen ReCoDe stands for REversing COgnitive DEcline. This completely personalized treatment program leans towards a ketogenic diet with modifications, requiring no pills or therapeutics.⁠

 

The Bredesen ReCoDe protocol is seeing amazing results in reversing Alzheimer’s cognitive decline. It is never too early to start looking after your brain. Take a look at some FAQs and sign up on the ReCoDe website here. The ReCoDe Report cannot be accessed outside of the United States. Patients must sign up for the REVERSE program, which is a subscription. Linden & Arc Vitality Institute provides patients with this fascinating protocol.

 

Alzheimer's Disease

Alzheimer’s ReCoDe

 

ReCoDe at Linden & Arc Vitality Institute

 

At Linden & Arc Vitality Institute, brain health matters. Dr. Bredesen’s ReCODE program is a treatment option at LMMD. As Dr. Nathan writes in the article, “Dr. Bredesen’s ReCODE program provides true hope for improvement and reversal of Alzheimer’s disease.”

 

At your initial consultation, we will gather your health history and family history. Every detail of your health through your life. We will pinpoint where the triggers to your current health may have come from. We gather more information and test you before populating the RECODE report. This allows us to prioritize your treatment. This will be a multidisciplinary approach. Nutritionists, exercise therapists, neural retraining, intravenous treatments, supplements, and meditation training are all possible aspects of your treatment.

 

Contact Linden & Arc Vitality Institute at [email protected] if you would like to learn more.