Regenerative Injection Techniques Explained

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Regenerative Injection Techniques (RIT) are a group of therapies first developed in the early 1900s. In many parts of the world, they are very commonly employed for treating pain, injury and degenerative changes in the musculoskeletal system. Some of these techniques have been utilized in the cosmetic industry as well.


Regenerative Injection Techniques have been developed by many doctors and treat many types of injuries such as nerves, muscles, and connective tissue injuries (tendons, ligaments and joints or cartilage).


Regenerative Injection Techniques include:


  • Prolotherapy
  • Neural therapy (NT)
  • Prolozone Therapy
  • Platelet-rich plasma (PRP)
  • Perineural subcutaneous injections
  • Mesotherapy
  • Myofascial trigger point injection (mTPI) 
  • Biopuncture


 Regenerative Injection Techniques are a simple, natural way of stimulating the body’s repair mechanism to heal. This is called the wound healing cascade. 



How do Regenerative Injection Techniques Work?


Natural ingredients or your blood create a mild inflammatory response that stimulates further regeneration and remodeling of the treated tissue. Your body responds by pulling in cells and substances of that wound healing cascade. Cells like platelets, white blood cells and even native stem cells. All these cells release growth factors that do the work. It is your body that heals itself.





Prolotherapy injections stimulate new cell growth and heal painful areas. These injections enhance the growth and formation of new ligaments, tendons, and cartilage in areas with scar tissue or weakness. They relieve pain by initiating your body’s natural healing process. Prolotherapy can treat back pain, sports injuries, fibromyalgia, arthritis, tendon injuries, and degenerative disk disease, among other things.



Neural Therapy 


Neural Therapy (NT) is a Regenerative Injection Technique that focuses on healing dysfunctions of the autonomic nervous system (ANS). NT removes neural interferences to normalize the ANS’s function and promote healthy signaling. Neural Therapy involves injections into nerve sites, glands, scars, and trigger points. This treatment can treat everything from chronic pain and illness to fatigue, digestive issues, and brain function.



Prolozone Therapy


Prolozone therapy combines neural therapy, prolotherapy, and ozone therapy. Ozone Therapy uses ozone gas to fight diseases and stimulate growth factors in the tissue surrounding an injured joint. Prolozone therapy is a great alternative to surgeries. These injections can subside joint pain naturally and strengthen damaged tissue.



Platelet-Rich Plasma Therapy


Platelet-Rich Plasma (PRP) is often used for healing musculoskeletal problems such as injured muscles, joints, tendons, ligaments and can even help with hair loss.


The treatment uses a patient’s blood cells to accelerate their body’s healing process. First, a small amount of the patient’s blood is collected. The platelets are then separated from the red blood cells and reintroduced to the patient via injection. The goal is to increase the concentration of growth factors to speed up the healing process.



Perineural Subcutaneous Injection Therapy


Perineural Subcutaneous Injection Therapy is a safe treatment for persistent pain. The injections go below the skin’s surface, reducing neurogenic inflammation in subcutaneous nerves that could be causing pain. Perineural Subcutaneous Injection Therapy helps with issues such as neuralgia, nerve impingement (pinched nerve), low back pain, fibromyalgia, shingles, and headaches/migraines.





Mesotherapy is a cosmetic surgery to help promote fat loss and cellulite. This therapy uses multiple tiny injections of vitamins, enzymes, and hormones into the middle layer of the skin. Mesotherapy helps to refresh and tighten skin and corrects poor circulation and inflammation.



Myofascial trigger point injection 


Myofascial trigger point injection (mTPI) is a treatment to help treat painful muscles containing trigger points or knots. Myofascial trigger points are focal knots in the skeletal muscle. These trigger points form when muscles stop relaxing. An mTPI treats fibromyalgia, tension headaches, myofascial pain, and calms muscles.





Biopuncture uses biotherapeutics, an active substance extracted from a biological source for injection into the body. These homeopathic compounds are injected into acupuncture points, trigger points, and pain points.


Biopuncture is often used in Functional Medicine to relieve neck, back, and shoulder pain, tendon and ligament injuries, sprains, osteoarthritis, tendonitis, tennis elbow, and muscle tears. It can also be used to alleviate other medical conditions including migraines, eczema, allergies, asthma, irritable bowel syndrome, and chronic fatigue syndrome. The injections are done in areas of pain and inflammation. This promotes a local immune response, stimulating healing and supporting the immune system.



What ingredients are used in Regenerative Injection Techniques? 


A local anesthetic, typically procaine or lidocaine, is commonly used in the base formula of Regenerative Injection Techniques. A local anesthetic does more than “freeze” the area, which is a nice benefit. Anesthetics have been shown to reset nerves malfunctioning due to traumas, allowing muscles to relax and initiate the movement of cells into the area. All these benefits tend to improve blood flow into the area. Improved blood flow brings in nutrients and oxygen and removes toxins (scar tissue). Anesthetics have also shown benefits in reducing the calcification of soft tissue. Think of calcific capsulitis and bone spurs.


The next most common ingredient is dextrose, a sugar. Dextrose is responsible for that proliferative response in tendons and ligaments. This result is the production of new collagen that, as it ages, will thicken or tighten tendons or ligaments that have become lax after an injury (strain or sprain). A tendon or ligament stretched beyond only 4% of its normal length will show permanent laxity unless treated. The repair of tendons and ligaments will result in a stabilizing effect on a joint. If a joint feels weak or susceptible to recurring injuries, these treatments will restore that youthful function. Dextrose, in very low doses (less than 5%), can act as an anesthetic that can reset nerves that are generating improper signals that register as pain.


There are several other ingredients that can be added to the base solution to give added benefit to the injection. Vitamin B12 can help with nerve issues such as carpal tunnel syndrome or sciatica. Studies have also shown an ability to reduce calcium deposits (pathological) in soft tissue. Adenosine Monophosphate (a naturally occurring compound associated with energy production) has been used to reduce those pesky calcium deposits. It is beneficial in reducing inflammation, such as bursitis, tendonitis and tenosynovitis. Ozone has been gaining a lot of attention. Studies completed in Italy have shown that adding ozone significantly improves the repair of herniated, bulging or desiccated discs of the spine.




How Regenerative Injection Techniques Can Help You


Injuries to tissues can sometimes lead to incomplete or inefficient healing due to poor blood flow, nutritional deficiencies, metabolic abnormalities or low oxygen states. These degenerative changes will register as pain typically but can also be felt as a reduced function of the soft tissue.


Have you ever felt that you cannot heal as fast as you used to or even not at all? Most current medical interventions, such as pain killers (anti- inflammatory drugs), muscle relaxants, or surgery, may be ineffective or unnecessary. Some of these approaches can even hinder or prevent the healing process from occurring. Studies are finding that corticosteroid injections can even hasten degenerative changes in joints.



Do Regenerative Injection Techniques Have Any Downsides?


For the most part, no. Since these techniques stimulate normal, healthy healing responses, treatment is typically well-tolerated.


Some conditions may reduce the effectiveness of treatment. Conditions, such as surgical metal implants, often restrict what can be done with Regenerative Injection Techniques. In very advanced cases of degeneration, surgery may still be required. You can try RIT prior to surgery to improve response and outcomes. A few techniques are still an option after surgery to speed up healing or reduce less than desirable outcomes, including Neural Therapy and Ozone Therapy.



Contact Linden & Arc Vitality Institute 


At Linden & Arc Vitality Institute, our Naturopathic approach to healing allows your body to restore itself physically, mentally, emotionally, and spiritually. We empower you with evidence-based natural treatments that support your body’s innate ability to heal, maintain health, and prevent disease. We are here to help you find freedom from pain and illness so you can return to feeling like yourself again.


If you think Regenerative Injection Techniques may be an option, contact Linden & Arc Vitality Institute HERE to get started on your transformative health journey.




Meet The Author


As one of the most enlightened naturopathic physicians, Dr. Trevor Hoffman brings an unparalleled passion to his work at Linden and Arc Vitality Institute.


Dr. Trevor Hoffman’s love of healing is part of his life’s purpose. With his vast experience and continuous endeavor to advance his practices, he is constantly seeking different ways of looking at health and wellness.


Dr. Trevor Hoffman is here to help transform your life through Naturopathic Medicine. To book an appointment with Dr. Trevor Hoffman, email [email protected]